統計、流病及EBM 5

CDC 的流病入門課程(pdf)，可以自己慢慢地自修。

American College of Physicians (ACP)所出版的好書

    Lang TA, Secic M: How to report statistics in medicine: annotated guidelines for authors, editors, and reviewers. Second edition. 2006; Philadelphia: American College of Physicians.

•         這本書教您如何報告醫學統計--值得擁有。缺點：未包括如何報告mixed model, GEE等較複雜方式。

    Lang的另一篇好文章：20個常見的統計錯誤
    Lang TA: Twenty statistical errors even you can find in biomedical research articles. Croat Med J. 2004;45:361-70.

免費的統計軟體

• John C. Pezzulo的著名網頁，可說是免費的統計軟體的大補帖，內含統計教學及線上統計軟體的相關連結。

統計學家Martin Bland的網站

• 許多好文章，可以進來挖寶。Bland-Altman Plot有詳細的說明。

線上生物統計

• GraphPad Quick Calcs
• 香港中文大學婦產科的線上生物統計(內含小小應用軟體可下載)
• VassarStats: Web Site for Statistical Computation
• Stats Calculator
• OpenEpi - The Epidemiology Calculator

天下文化出版的書籍，可說是本本精彩

1. 史密斯(Woollcott Smith) 著, 鄭惟厚 譯, 高尼克(Larry Gonick) 繪. 看漫畫，學統計 The Cartoon Guide to Statistics. 台北: 天下文化, 2003.
2. 墨爾(David S. Moore) 著, 鄭惟厚 譯. 統計，讓數字說話! STATISTICS. 台北: 天下文化, 1998.
3. 墨爾(David S. Moore) 著, 鄭惟厚 譯. 統計學的世界Statistics, concepts and controversies, 5th ed. 台北: 天下文化, 2002.
4. 拉森(Harold J. Larson) 著, 鄭惟厚 譯. 機率學的世界 Introduction to Probability. 台北: 天下文化, 2004.
5. 瓊斯 (Gerald Everett Jones) 著, 葉偉文 譯. 別讓統計圖表唬弄你 How to Lie with Charts. 台北: 天下文化, 2005.
6. 萊文森(Horace C. Levinson) 著, 葉偉文 譯. 統計你贏的機率 Chance, Luck, and Statistics. 台北: 天下文化, 2004.
7. 薩爾斯伯格(David Salsburg) 著, 葉偉文 譯. 統計，改變了世界The Lady Tasting Tea. 台北: 天下文化, 2001.
8. 赫夫(Darrell Huff) 著, 鄭惟厚 譯, 蓋斯(Irving Geis) 繪. 別讓統計數字騙了你 How to Lie with Statistics. 台北: 天下文化, 2005.

統計、流病及EBM 4

Aviva Petrie 等人在British Dentistry Journal上的文章(Aviva Petrie即是Medical Statistics at a Glance的作者之一)

1. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry: Part 1: Research designs 1. Br Dent J 2002;193:377-380.
2. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry. Part 2: Research designs 2. Br Dent J 2002;193:435-440.
3. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry. Part 3: Clinical trials 1. Br Dent J 2002;193:495-498.
4. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry. Part 4: Clinical trials 2. Br Dent J 2002;193:557-561.
5. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry, Part 5: Diagnostic tests for oral conditions. Br Dent J 2002;193:621-625.
6. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry. Part 6: Multiple linear regression. Br Dent J 2002;193:675-682.
7. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry. Part 7: repeated measures. Br Dent J 2003;194:17-21.
8. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry, Part 8: Systematic reviews and meta-analyses. Br Dent J 2003;194:73-78.
9. Petrie A, Bulman JS, Osborn JF: Further statistics in dentistry. Part 9: Bayesian statistics. Br Dent J 2003;194:129-134.
10. Osborn JF, Bulman JS, Petrie A: Further statistics in dentistry. Part 10: Sherlock Holmes, evidence and evidence-based dentistry. Br Dent J 2003;194:189-195.

BMJ (British medical journal)

• 統計教學當然不可遺漏BMJ的好站 Statistics at Square One
• 入門者的流行病學 Epidemiology for the Uninitiated
• 如何閱讀期刊論文 How to read a paper: the basic of evidence-based medicine

統計、流病及EBM 3

在American Journal of Roentgenology 上關於統計的文章

1. Beam CA, Blackmore CC, Karlik S, Reinhold C. Editors' Introduction to the Series. Am. J. Roentgenol. 2001; 176:323-325.
2. Blackmore CC. The Challenge of Clinical Radiology Research. Am. J. Roentgenol. 2001; 176:327-331.
3. Crewson PE, Applegate KE. Data Collection in Radiology Research. Am. J. Roentgenol. 2001; 177:755-761.
4. Jarvik JG. The Research Framework. Am. J. Roentgenol. 2001; 176:873-878.
5. Saini S. Radiologic Measurement of Tumor Size in Clinical Trials: Past, Present, and Future. Am. J. Roentgenol. 2001; 176:333-334.
6. Beam CA. Statistically Engineering the Study for Success. Am. J. Roentgenol. 2002; 179:47-52.
7. Joseph L, Reinhold C. Introduction to Probability Theory and Sampling Distributions. Am. J. Roentgenol. 2003; 180:917-923.
8. Karlik SJ. Exploring and Summarizing Radiologic Data. Am. J. Roentgenol. 2003; 180:47-54.
9. Karlik SJ. Visualizing Radiologic Data. Am. J. Roentgenol. 2003; 180:607-619.
10. Blackmore CC, Cummings P. Observational Studies in Radiology. Am. J. Roentgenol. 2004; 183:1203-1208.
11. Crewson PE. Reader Agreement Studies. Am. J. Roentgenol. 2005; 184:1391-1397.
12. Dendukuri N, Reinhold C. Correlation and Regression. Am. J. Roentgenol. 2005; 185:3-18.
13. Joseph L, Reinhold C. Statistical Inference for Continuous Variables. Am. J. Roentgenol. 2005; 184:1047-1056.
14. Joseph L, Reinhold C. Statistical Inference for Proportions. Am. J. Roentgenol. 2005; 184:1057-1064.
15. Obuchowski NA. Multivariate Statistical Methods. Am. J. Roentgenol. 2005; 185:299-309.
16. Obuchowski NA. ROC Analysis. Am. J. Roentgenol. 2005; 184:364-372.
17. Plevritis SK. Decision Analysis and Simulation Modeling for Evaluating Diagnostic Tests on the Basis of Patient Outcomes. Am. J. Roentgenol. 2005; 185:581-590.
18. Stolberg HO, Norman G, Trop I. Survival Analysis. Am. J. Roentgenol. 2005; 185:19-22.
19. Weinstein S, Obuchowski NA, Lieber ML. Clinical Evaluation of Diagnostic Tests. Am. J. Roentgenol. 2005; 184:14-19.
20. Willis CE, Slovis TL. The ALARA Concept in Pediatric CR and DR: Dose Reduction in Pediatric Radiographic Exams -- A White Paper Conference. Am. J. Roentgenol. 2005; 184:373-374.
21. Gatsonis C, Paliwal P. Meta-Analysis of Diagnostic and Screening Test Accuracy Evaluations: Methodologic Primer. Am. J. Roentgenol. 2006; 187:271-281.

統計、流病及EBM 2

在Clinical Orthopaedics and Related Research上關於統計、流病及EBM的文章 (因CORR改由Springer發行，但Springer只有2008年以後的版權，目前連結重新製作中)

1. Schunemann HJ, Bone L. Evidence-based orthopaedics: a primer. Clin Orthop 2003(413):117-32.
2. Montori VM, Swiontkowski MF, Cook DJ. Methodologic issues in systematic reviews and meta-analyses. Clin Orthop 2003(413):43-54.
3. Mitchell SW. The history of instrumental precision in medicine. Univ Med Magazine, October 1841. Clin Orthop 2003(413):11-8; discussion.
4. Kocher MS, Henley MB. It is money that matters: decision analysis and cost-effectiveness analysis. Clin Orthop 2003(413):106-16.
5. Jackowski D, Guyatt G. A guide to health measurement. Clin Orthop 2003(413):80-9.
6. Hartz A, Marsh JL. Methodologic issues in observational studies. Clin Orthop 2003(413):33-42.
7. Griffin D, Audige L. Common statistical methods in orthopaedic clinical studies. Clin Orthop 2003(413):70-9.
8. Gillespie LD, Gillespie WJ. Finding current evidence: search strategies and common databases. Clin Orthop 2003(413):133-45.
9. Dirschl DR, Tornetta P 3rd, Bhandari M. Designing, conducting, and evaluating journal clubs in orthopaedic surgery. Clin Orthop 2003(413):146-57.
10. Devereaux PJ, McKee MD, Yusuf S. Methodologic issues in randomized controlled trials of surgical interventions. Clin Orthop 2003(413):25-32.
11. Brighton B, Bhandari M, Tornetta P 3rd, Felson DT. Hierarchy of evidence: from case reports to randomized controlled trials. Clin Orthop 2003(413):19-24.
12. Bhandari M, Whang W, Kuo JC, Devereaux PJ, Sprague S, Tornetta P 3rd. The risk of false-positive results in orthopaedic surgical trials. Clin Orthop 2003(413):63-9.
13. Bhandari M, Tornetta P 3rd, Guyatt GH. Glossary of evidence-based orthopaedic terminology. Clin Orthop 2003(413):158-63.
14. Bhandari M, Tornetta P 3rd. Evidence-based orthopaedics: a paradigm shift. Clin Orthop 2003(413):9-10.
15. Bernstein J, McGuire K, Freedman KB. Statistical sampling and hypothesis testing in orthopaedic research. Clin Orthop 2003(413):55-62.
16. Beaton DE, Schemitsch E. Measures of health-related quality of life and physical function. Clin Orthop 2003(413):90-105.

統計、流病及EBM 1

以下是以前所收集的文章及網頁，分享給各位：

Tufts University 的 Gerard E. Dallal, PhD 所編纂的 BMJ (British Medical Journal) statistics note (整理的相當好)

在Radiology上有一系列關於統計的文章，內容相當新。值得花時間仔細閱讀。Radiology也整理出稿件中十大常見統計錯誤。

在Journal of Bone and Joint Surgery American Edition, British Edition 及Instructional Course Lecture上關於統計及流病的文章

1. Bubbar VK, Kreder HJ: The intention-to-treat principle: a primer for the orthopaedic surgeon. J Bone Joint Surg Am 2006;88:2097-2099.
2. Petrie A: Statistics in orthopaedic papers. J Bone Joint Surg Br 2006;88:1121-1136.
3. Kocher MS, Zurakowski D. Clinical epidemiology and biostatistics: a primer for orthopaedic surgeons. J Bone Joint Surg Am 2004; 86:607-620.
4. Bhandari M, Richards RR, Sprague S, Schemitsch EH. The quality of reporting of randomized trials in the Journal of Bone and Joint
   Surgery from 1988 through 2000. J Bone Joint Surg Am. 2002;84:388-96.
5. Bhandari M, Morrow F, Kulkarni AV, Tornetta P 3rd. Meta-analyses in orthopaedic surgery. A systematic review of their methodologies. J Bone Joint Surg Am. 2001;83:15-24.
6. Bhandari M, Guyatt GH, Montori V, Devereaux PJ, Swiontkowski MF. User's guide to the orthopaedic literature: how to use a systematic literature review. J Bone Joint Surg Am. 2001;83:1650-5.
7. Lochner HV, Bhandari M, Tornetta P 3rd. Type-II error rates (beta errors) of randomized trials in orthopaedic trauma. J Bone Joint Surg Am. 2001;83:1650-5.
8. Freedman KB, Back S, Bernstein J. Sample size and statistical power of randomised, controlled trials in orthopaedics. J Bone Joint Surg Br 2001; 83:397-402.
9. Freedman KB, Bernstein J. Sample size and statistical power in clinical orthopaedic research. J Bone Joint Surg Am 1999; 81:1454-1460.
10. Szabo RM. Principles of epidemiology for the orthopaedic surgeon. J Bone Joint Surg Am 1998; 80:111-120.
11. Smith JS, Watts HG. Methods for locating missing patients for the purpose of long-term clinical studies. J Bone Joint Surg Am 1998; 80:431-438.
12. Fuson RL, Sherman M, Van Vleet J, Wendt T. The conduct of orthopaedic clinical trials. J Bone Joint Surg Am. 1997; 79:1089-98.
13. Ebramzadeh E, McKellop H, Dorey F, Sarmiento A. Challenging the validity of conclusions based on P-values alone: a critique of contemporary clinical research design and methods. Instr Course Lect 1994; 43:587-600.
14. Dorey F, Nasser S, Amstutz H. The need for confidence intervals in the presentation of orthopaedic data. [PDF] J Bone Joint Surg Am 1993; 75:1844-1852.  
15. Dorey F, Amstutz HC. Discrepancies in the orthopaedic literature: why? A statistical explanation. Instr Course Lect 1993; 42:555-564.
16. Santner TJ, Wypij D. Fundamentals of statistics for orthopaedists: Part IV. [PDF] J Bone Joint Surg Am 1987; 69:463-470.  
17. Santner TJ, Wypij D. Fundamentals of statistics for orthopaedists: Part III. [PDF] J Bone Joint Surg Am 1984; 66:1309-1318.  
18. Santner TJ, Burstein AH. Fundamentals of statistics for orthopaedists: Part II. [PDF] J Bone Joint Surg Am 1984; 66:794-799.  
19. Santner TJ. Fundamentals of statistics for orthopaedists: Part I. [PDF] J Bone Joint Surg Am 1984; 66:468-471.

Page one, page one, page one, page nothing.

"Page one, page one, page one, page nothing." says Quido Contini in the movie "Nine". 在電影華麗年代中， 大導演Quido為寫不出劇本而苦惱。